Published Research Papers
We have more than a decade’s worth of data on our stem cell procedures, and our patients are participants in the largest human mesenchymal stem cell (MSC) orthopedic re-implantation database in the world. Because of our long history in the field and commitment to research, Regenexx® has more data than any of our peer orthopedic stem cell providers. We analyze and report on outcome data from our patient registry on a regular basis and publish our findings in medical journals for our peers and patients to learn more about this growing practice.
Medical Journal Articles Containing Regenexx Research
- Quantitation of progenitor cell populations and growth factors after bone marrow aspirate concentration.
Journal of Translational Medicine - Platelet lysates from aged donors promote human tenocyte proliferation and migration in a concentrationdependent manner
Bone & Joint Research - Quantitation of progenitor cell populations and growth factors after bone marrow aspirate concentration.
Journal of Translational Medicine - Platelet lysates from aged donors promote human tenocyte proliferation and migration in a concentration-dependent manner.
Bone & Joint Research. (2019) - A specific protocol of autologous bone marrow concentrate and platelet products versus exercise therapy for symptomatic knee osteoarthritis; a randomized control trial with 2 year follow-up.
Journal of Translational Medicine - A multi-center analysis of adverse events among two thousand, three hundred and seventy two adult patients undergoing adult autologous stem cell therapy for orthopaedic conditions.
International Orthopaedics - Symptomatic anterior cruciate ligament tears treated with percutaneous injection of autologous bone marrow concentrate and platelet products: a non-controlled registry study.
Journal of Translational Medicine (2018) - Treatment of lumbar degenerative disc disease-associated radicular pain with culture-expanded autologous mesenchymal stem cells: a pilot study on safety and efficacy.
Journal of Translational Medicine (2017) - The use of lumbar epidural injection of platelet lysate for treatment of radicular pain.
Journal of Experimental Orthopaedics (2017) - A New Atlanto-Occipital (C0-C1) Joint Injection Technique
Pain Medicine (2017) - Interventional Orthopedics in Pain Medicine Practice
Techniques in Regional Anesthesia and Pain Management - Intra-discal injection of autologous, hypoxic cultured bone marrow-derived mesenchymal stem cells in five patients with chronic lower back pain: a long-term safety and feasibility study.
Journal of Translational Medicine (2016) - Performing a Better Bone Marrow Aspiration.
Physical Medicine and Rehabilitation Clinics of North America (2016) - A Dose Response Analysis of a Specific Bone Marrow Concentrate Treatment Protocol for Knee Osteoarthritis.
BMC Musculoskeletal Disorders (2015) - Anterior Cruciate Ligament (ACL) Tears treated with Percutaneous Injection of Autologous Bone Marrow Nucleated Cells: A Case Series.
Journal of Pain Research 2015: 8: 437-447 - Efficacy and Safety of Bone Marrow Concentrate for Osteoarthritis of the Hip; Treatment Registry Results for 196 Patients.
Stem Cell Research and Therapy; Volume 4: Issue 10; 2014, Article ID 370621,. Centeno CJ. - Efficacy of Autologous Bone Marrow Concentrate for Knee Osteoarthritis with and without Adipose Graft.
BioMed Research International; Volume 2014, Article ID 370621,. Centeno CJ. - A Prospective Multi-site Registry Study of a Specific Protocol of Autologous Bone Marrow Concentrate for the Treatment of Shoulder Rotator Cuff Tears and Osteoarthritis.
Journal of Pain Research 2015:8 269–276 - Amide-Type Local Anesthetics and Human Mesenchymal Stem Cells: Clinical Implications for Stem Cell Therapy.
Stem Cells Transl Med. 2014 Jan 16. - Increased knee cartilage volume in degenerative joint disease using percutaneously implanted, autologous mesenchymal stem cells.
Regenerative Sciences Inc (RSI), Centeno-Schultz Clinic, Westminster, CO 80020, USA.–Pain Physician. 2008 May-Jun;11(3):343-53. - Clinical challenges and opportunities of mesenchymal stem cells in musculoskeletal medicine.
PM R. 2014 Jan;6(1):70-7. doi: 10.1016/j.pmrj.2013.08.612. Centeno CJ. - Percutaneous injection of autologous, culture-expanded mesenchymal stem cells into carpometacarpal hand joints: a case series with an untreated comparison group.
Wien Med Wochenschr. 2013 Aug 15. - Safety and Complications Reporting Update on the Re-implantation of Culture-Expanded Mesenchymal Stem Cells using Autologous Platelet Lysate Technique.
Centeno CJ, Schultz JR, Cheever M, Freeman M, Faulkner S, Robinson B, Hanson R.–Curr Stem Cell Res Ther. 2011 Oct 17. - A Case Series of Percutaneous Treatment of Non-Union Fractures with Autologous, Culture Expanded, Bone Marrow Derived, Mesenchymal Stem Cells and Platelet Lysate
Journal of Bioengineering and Biomedical Science. 2011 - Osteoblastic differentiation of human and equine adult bone marrow-derived mesenchymal stem cells when BMP-2 or BMP-7 homodimer genetic modification is compared to BMP-2/7 heterodimer genetic modification in the presence and absence of dexamethasone.
J Orthop Res. 2010 Mar 22 - Safety and complications reporting on the re-implantation of culture-expanded mesenchymal stem cells using autologous platelet lysate technique.
Curr Stem Cell Res Ther. 2010 Mar;5(1):81-93. - Regeneration of meniscus cartilage in a knee treated with percutaneously implanted autologous mesenchymal stem cells.
Med Hypotheses. 2008 Dec;71(6):900-8. Epub 2008 Sep 10. - Partial regeneration of the human hip via autologous bone marrow nucleated cell transfer: A case study.
Pain Physician. 2006 Jul;9(3):253-6.